DSF Transformational Science Grants

Transformational Science Grant Awards are the largest grants awarded by DSF. Transformational Science Grants are intended for established, experienced, independent investigators affiliated with a research or academic institution whose proposed projects investigate hypotheses directly related to Dravet syndrome. Transformational Science Grants should have substantial preliminary data to support the stated hypothesis and strong potential to significantly impact the research field or move the needle on clinical care. Proposals are scored according to NIH guidelines based on the quality of preliminary data, research design, feasibility, investigator’s qualifications, and overall impact. Grants are awarded for $500,000 over 3 years (beginning January 1 of each year). Indirect costs must be included within the $500,00 budget and are not to exceed 10% of the total award.

Investigators applying for a DSF grant should ensure their proposed project addresses the needs of the Dravet syndrome community and DSF’s mission to support research toward better treatments and a cure for Dravet syndrome. Proposals should address research areas related to the DSF's yearly priority areas and DSF’s Roadmap to a Cure.

Eligibility: Applicants should be affiliated with a research or academic institution (excluding for-profit companies), may be US or foreign based, established in their field, and in good standing with their institution.

Tags: Dravet Syndrome, SCN1A, Models, Clinical Epilepsy, Mechanisms, Human Studies, Devices, Technologies, Stem Cells, Biomarkers, Behavior, Neuropsychology, Language, Genetics, Comorbidity (Somatic and Psychiatric), Antiepileptic Drugs, Non-AED, Non-Surgical Treatments , SUDEP